Publications
Brown ME, Zhou Y, McIntosh BE, Norman IG, Lou HE, Biermann M, Sullivan JA, Kamp TJ, Thomson JA, Anagnostopoulos PV, Burlingham WJ. A Humanized Mouse Model Generated Using Surplus Neonatal Tissue. Stem Cell Reports 2018 Apr 10;10(4):1175-1183.
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Ling C, Li Q, Brown ME, Kishimoto Y, Toya Y, Devine EE, Choi KO, Nishimoto K, Norman IG, Tsegyal T, Jiang JJ, Burlingham WJ, Gunasekaran S, Smith LM, Frey BL, Welham NV. Bioengineered vocal fold mucosa for voice restoration. Sci Transl Med 2015 Nov 18;7(314):314ra187.
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McIntosh BE, Brown ME. No irradiation required: The future of humanized immune system modeling in murine hosts. Chimerism 2015 Apr 3;6(1-2):40-5.
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McIntosh BE, Brown ME, Duffin BM, Maufort JP, Vereide DT, Slukvin II, Thomson JA. Nonirradiated NOD,B6.SCID Il2rγ-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells. Stem Cell Reports 2015 Feb 10; 4(2):171-80.
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Lockridge JL, Zhou Y, Becker YA, Ma S, Kenney SC, Hematti P, Capitini CM, Burlingham WJ, Gendron-Fitzpatrick A, Gumperz JE. Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease. Biol. Blood Marrow Transplant. 2013 Sep; 19(9):1310-22.
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Ma SD, Yu X, Mertz JE, Gumperz JE, Reinheim E, Zhou Y, Tang W, Burlingham WJ, Gulley ML, Kenney SC. An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. J. Virol. 2012 Aug; 86(15):7976-87.
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Kalscheuer H, Danzl N, Onoe T, Faust T, Winchester R, Goland R, Greenberg E, Spitzer TR, Savage DG, Tahara H, Choi G, Yang YG, Sykes M. A model for personalized in vivo analysis of human immune responsiveness. Sci Transl Med 2012 Mar 14; 4(125):125ra30
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Lockridge JL, Chen X, Zhou Y, Rajesh D, Roenneburg DA, Hegde S, Gerdts S, Cheng TY, Anderson RJ, Painter GF, Moody DB, Burlingham WJ, Gumperz JE. Analysis of the CD1 antigen presenting system in humanized SCID mice. PLoS ONE 2011; 6(6):e21701.
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Ma SD, Hegde S, Young KH, Sullivan R, Rajesh D, Zhou Y, Jankowska-Gan E, Burlingham WJ, Sun X, Gulley ML, Tang W, Gumperz JE, Kenney SC. A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas. J. Virol. 2011 Jan; 85(1):165-77.
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Rajesh D, Zhou Y, Jankowska-Gan E, Roenneburg DA, Dart ML, Torrealba J, Burlingham WJ. Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rgammanull mice. Hum. Immunol. 2010 Jun; 71(6):551-9.
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Lan P, Tonomura N, Shimizu A, Wang S, Yang YG. Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation. Blood 2006 Jul 15; 108(2):487-92.
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Funding
The Humanized Mouse Core is funded by fees for service. Additionally, the Core is generously supported by the University of Wisconsin Department of Surgery, the School of Medicine and Public Health, University of Wisconsin Department of Medicine [hyperlink to http://www.medicine.wisc.edu/ ], and the UW Stem Cell and Regenerative Medicine Center.
The content of this website is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.